FAQs

MacuDopa contains Mucuna pruriens, also known as velvet bean or cowhage. It is a tropical legume plant native to India, Africa, and the Caribbean. It has been used for centuries in traditional Ayurvedic medicine to support a variety of conditions, including low dopamine states like Parkinson's disease. The plant contains natural L-DOPA, the precursor to the neurotransmitter dopamine. Dopamine is a crucial neurotransmitter involved in several physiological functions, including movement, mood regulation, and motivation. As a result, Mucuna Pruriens has gained attention for its use as a support for low dopamine states like Parkinson's disease, a condition characterised by a loss of dopamine-producing neurons in the brain. In addition, Mucuna Pruriens has also been found to have antioxidant and anti-inflammatory properties. These properties may be beneficial in reducing oxidative stress and inflammation, which are associated with several chronic diseases, including Alzheimer's disease and heart disease. Mucuna pruriens has the added benefit of reducing your chances of developing dyskinesia in the longer term. Take a look at the science paper that supports this. Our MacuDopa contains the very highest quality HPLC standardised practitioner grade Mucuna pruriens. Please consult your doctor or neurologist before taking MacuDopa. NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

MacuDopa Day Start with 1 capsule and adjust the intake up as needed to fully manage your symptoms, or take as recommended by your doctor or practitioner. The average client uses 14 capsules a day but you are unique and may use a lot less or need a lot more to start with. Those who are older and have more established symptoms often need a large loading dose for a few weeks and then reduce the dose down. Read the 'How to take MacuDopa' page on our site. MacuDopa Night Start with 1 delayed-release capsule last thing at night and adjust as needed (to a maximum of 2 per night), or take as recommended by your doctor or practitioner. If you have an existing condition or are on any medication please check with your doctor or health professional BEFORE taking MacuDopa. VIP: Do not take MacuDopa 30 minutes before or for 30 minutes after a strong protein meal (meat, fish, chicken, tofu and so on). To get the best support from MacuDopa visit our 'How to take MacuDopa' page and learn how to stay 'ON'. Stay in the green: NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

If you are on an any existing pharmaceutical medication you MUST speak to your doctor or health practitioner BEFORE taking MacuDopa. NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

We recommend you take enough to fully manage your symptoms. This is entirely dependant on your unique individual needs. Some clients use 1 capsule every 3 hours, others use 3 capsules every 2 hours, whilst other use a large dose to start with (for a few weeks) and then reduce the dose as the MacuDopa starts to impact. You are in charge. If you feel nauseous reduce your dose as this is a sign that you have had a little too much. Visit the 'How to take MacuDopa' page on our site to better understand the concept of 'staying ON'. NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

MacuDopa night is manufactured using delayed-release capsules. This means that when you take a capsule before bed, the Mucuna is released an hour or more after taking it. This ensures that you maintain some of the supportive effect through the night. The day capsules, on the other hand, break down quickly to release the supportive benefits of MacuDopa. Our MacuDopa Day and Night contains HPLC standardised practitioner grade Mucuna pruriens. NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

L-DOPA (levodopa) crosses the blood brain barrier naturally. Specifically, levodopa is transported across the blood-brain-barrier (BBB) by the large neutral amino acid transporter (LAT1), which is expressed on the endothelial cells. In standard Parkinson's pharmaceutical medicines, there are two inhibitors : in carbidopa (combined with levodopa as co-careldopa) and benserazide (combined with levodopa as co-beneldopa). These inhibit the peripheral metabolism of levodopa, ie: stop it from working on the body and causing nausea and increases the amount that crosses the blood–brain barrier to 5–10% of the oral dose. Mucuna also contains natural phytochemicals that assist in the absorption and action on the brain. Two interesting studies: https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1099-1573(199709)11:6%3C419::AID-PTR120%3E3.0.CO;2-Q https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1738871/pdf/v075p01672.pdf NOTE: This website is for customers in the United States of America and worldwide only. If you are a UK citizen looking to buy Macudopa please visit our UK site. ​ All the information included on this website is for information purposes only. It is not intended to treat or diagnose any medical condition, nor is it intended as a substitute for medical advice. We do not suggest using Mucuna pruriens to treat Parkinson's unless prescribed by your medical professional. If you are concerned about any symptoms please visit your doctor for investigation and diagnosis. For medical diagnosis and treatment please consult your specialist or doctor.

At MacuDopa we have the deepest respect for the work on The US PD association. We regularly send the following essay to our clients and to Max's patients: https://www.apdaparkinson.org/article/mucuna-pruriens-for-parkinsons-disease/